VARIANTPlex

LOW INPUT

AMP chemistry was purpose-build for library prep from low-input and degraded samples such as FFPE tissue. Compatible with blood and bone marrow input types

SENSITIVE & SPECIFIC VARIANT DETECTION

error connection features within Archer reduce sequencer noise to reveal mutations below standard NGS-based detection threshold

QUANTITATIVE

CNV DETECTION

Molecular bar coded fragments counting provides robust copy number analysis

COMPREHENSIVE COVERAGE

AMP chemistry provides complete, strand-specific and bi-directional coverage of target exons to maximize variant detection

COMPLEX MUTATION DETECTION

Coverage combined with powerful bioinformatics enables mutation detection in traditionally difficult regions like CEBPA & FLT3

CUSTOMIZATION

Create from scratch or modify any panel to keep up with the pace of discovery 

 

The VariantPlex CFTR panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex Reagents (SK0096, SK0098) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of all exons of the Cystic Fibrosis Conductance Regulator (CFTR) gene, including 5’ and 3’ untranslated regions (UTRs). VariantPlex CFTR libraries contain 105 GSP2 primers with coverage of select intronic variants.

Platform

Description

Part Number

Storage Condition

Illumina®

VariantPlex® CFTR GSP1 - 8 reactions

SA0079-8-1

VariantPlex® CFTR GSP2 - 8 reactions

SA0079-8-2

-20°C ± 10°C

 

The VariantPlex CTL panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex HS Reagents for Illumina® (SK0117) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of 290 regions of interest across 31 genes frequently mutated in NSCLC and thyroid cancer.

Platform

Description

Part Number

Storage Condition

VariantPlex® CTL GSP1 - 8 reactions

VariantPlex® CTL GSP2 - 8 reactions

Illumina®

-20°C ± 10°C

SA0071082

SA0071081

Archer® PreSeq™ DNA QC Assay Standard

SA0597

Archer® PreSeq™ DNA QC Assay 10x Primer Mix

SA0598

 

The Archer® VariantPlex Core Myeloid panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex HGC Reagents for Illumina® (SK0115) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of 37 genes frequently mutated in myeloid malignancies.

Platform

Description

Part Number

Storage Condition

Illumina®

VariantPlex® Core Myeloid GSP1 - 8 reactions

VariantPlex® Core Myeloid GSP2 - 8 reactions

SA5030082

SA5030081

PreSeq® DNA QC Assay Standard - 32 µL

SA0597

PreSeq® DNA QC Assay 10X Primer Mix - 120 µL

SA0598

-20°C ± 10°C

 

The VariantPlex Myeloid panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex HGC Reagents for Illumina® (SK0115) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of 75 genes frequently mutated in myeloid malignancies.

Platform

Description

Part Number

Storage Condition

Illumina®

VariantPlex® Myeloid GSP1 - 8 reactions

VariantPlex® Myeloid GSP2 - 8 reactions

SA5031082

SA5031081

PreSeq® DNA QC Assay Standard - 32 µL

SA0597

PreSeq DNA QC Assay Standard - 32 µL

SA0598

-20°C ± 10°C

 

The VariantPlex Solid Tumor panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex HS Reagents for Illumina® (SK0117) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of 660 regions of interest across 67 genes frequently mutated in a broad spectrum of solid tumor-type malignancies.

Platform

Description

Part Number

Storage Condition

VariantPlex® Solid Tumor GSP1 - 8 reactions

VariantPlex® Solid Tumor GSP2 - 8 reactions

SA0193

SA0192

SA0597

Archer® PreSeq™ DNA QC Assay 10x Primer Mix

Illumina®

Archer® PreSeq™ DNA QC Assay Standard

SA0598

-20°C ± 10°C

0. Neoscience logo with tagline.png

+603-7610 0388

Unit C109-110, Level 1, Block C,

Kelana Square,

17, Jalan SS7/26, Kelana Jaya,

47301 Petaling Jaya, Selangor, Malaysia.

Subscribe For Updates

Follow Us

  • Twitter
  • LinkedIn
  • Facebook - White Circle
  • Instagram