LOW INPUT
AMP chemistry was purpose-build for library prep from low-input and degraded samples such as FFPE tissue. Compatible with blood and bone marrow input types
SENSITIVE & SPECIFIC VARIANT DETECTION
error connection features within Archer reduce sequencer noise to reveal mutations below standard NGS-based detection threshold
QUANTITATIVE
CNV DETECTION
Molecular bar coded fragments counting provides robust copy number analysis
COMPREHENSIVE COVERAGE
AMP chemistry provides complete, strand-specific and bi-directional coverage of target exons to maximize variant detection
COMPLEX MUTATION DETECTION
Coverage combined with powerful bioinformatics enables mutation detection in traditionally difficult regions like CEBPA & FLT3
CUSTOMIZATION
Create from scratch or modify any panel to keep up with the pace of discovery
VariantPlex® CFTR
The VariantPlex CFTR panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex Reagents (SK0096, SK0098) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of all exons of the Cystic Fibrosis Conductance Regulator (CFTR) gene, including 5’ and 3’ untranslated regions (UTRs). VariantPlex CFTR libraries contain 105 GSP2 primers with coverage of select intronic variants.
Platform
Description
Part Number
Storage Condition
Illumina®
VariantPlex® CFTR GSP1 - 8 reactions
SA0079-8-1
VariantPlex® CFTR GSP2 - 8 reactions
SA0079-8-2
-20°C ± 10°C
VariantPlex® Comprehensive Thyroid and Lung (CTL)
The VariantPlex CTL panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex HS Reagents for Illumina® (SK0117) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of 290 regions of interest across 31 genes frequently mutated in NSCLC and thyroid cancer.
Platform
Description
Part Number
Storage Condition
VariantPlex® CTL GSP1 - 8 reactions
VariantPlex® CTL GSP2 - 8 reactions
Illumina®
-20°C ± 10°C
SA0071082
SA0071081
Archer® PreSeq™ DNA QC Assay Standard
SA0597
Archer® PreSeq™ DNA QC Assay 10x Primer Mix
SA0598
VariantPlex® Core Myeloid
The Archer® VariantPlex Core Myeloid panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex HGC Reagents for Illumina® (SK0115) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of 37 genes frequently mutated in myeloid malignancies.
Platform
Description
Part Number
Storage Condition
Illumina®
VariantPlex® Core Myeloid GSP1 - 8 reactions
VariantPlex® Core Myeloid GSP2 - 8 reactions
SA5030082
SA5030081
PreSeq® DNA QC Assay Standard - 32 µL
SA0597
PreSeq® DNA QC Assay 10X Primer Mix - 120 µL
SA0598
-20°C ± 10°C
VariantPlex® Myeloid
The VariantPlex Myeloid panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex HGC Reagents for Illumina® (SK0115) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of 75 genes frequently mutated in myeloid malignancies.
Platform
Description
Part Number
Storage Condition
Illumina®
VariantPlex® Myeloid GSP1 - 8 reactions
VariantPlex® Myeloid GSP2 - 8 reactions
SA5031082
SA5031081
PreSeq® DNA QC Assay Standard - 32 µL
SA0597
PreSeq DNA QC Assay Standard - 32 µL
SA0598
-20°C ± 10°C
VariantPlex® Solid Tumor
The VariantPlex Solid Tumor panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with VariantPlex HS Reagents for Illumina® (SK0117) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of 660 regions of interest across 67 genes frequently mutated in a broad spectrum of solid tumor-type malignancies.
Platform
Description
Part Number
Storage Condition
VariantPlex® Solid Tumor GSP1 - 8 reactions
VariantPlex® Solid Tumor GSP2 - 8 reactions
SA0193
SA0192
SA0597
Archer® PreSeq™ DNA QC Assay 10x Primer Mix
Illumina®
Archer® PreSeq™ DNA QC Assay Standard
SA0598
-20°C ± 10°C
