LIQUIDPlex
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RELEVANT FRAGMENT CAPTURE

AMP based target enrichment preferentially enriches for highly fragmented ctDNA over genomic cell-free DNA (cDNA) to reduce background noise and increase detection sensitivity of low allelic frequency (AF) mutations. 

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SINGLE-DAY LIBRARY PREP

NGS- ready libraries can be prepared in under 8 hours with less than 1 hour of hands-on time, providing sequencing results in as little as 3 days.

ERROR CORRECTION & QUANTITATIVE ANALYSIS

molecular bar coded adapters ligated prior to amplification enable duplicate read binning and advance error correction for confident variant calls

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SENSITIVE & ROBUST VARIANT DETECTION

reliably detect high AF (5%) variants using as little as 5ng total ctDNA input and low AF (1%) variants from as little as 10ng

 

LiquidPlex™

The LiquidPlex ctDNA 28 panel is an optimized balance of gene-specific primer (GSP) oligonucleotides that is used in conjunction with LiquidPlex Reagents (SK0119) or VariantPlex® Somatic Reagents (SK0117) and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries of 28 genes frequently mutated in solid tumor type cancers.

Platform

Description

Part Number

Storage Condition

Illumina®

LiquidPlex GSP1 - 8 reactions

SA0095081

LiquidPlex GSP2 - 8 reactions

SA0095082

-20°C ± 10°C