FUSIONPlex

NOVEL FUSIONS

AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the partner is known.

LOW INPUT

AMP chemistry was purpose-build for library prep from low-input and degraded samples such as FFPE tissue

SPLICE VARIANTS & ISOFORMS OF INTEREST

detect cancer-associated events such as METex14 skipping, EGFRviii or kinase domain duplications.

QUIVER FUSION DATABASE

powerful fusion analysis combined with a curated database of relevent known translocations

EXPRESSION

Molecular bar coded fragments enable accurate RNA abundance calculations

CUSTOMIZATION

Create from scratch or modify any panel to keep up with the pace of discovery

FusionPlex® Lymphoma

FusionPlex® Myeloid

FusionPlex® Oncology Research

FusionPlex® Pan-Heme

FusionPlex® Sarcoma

FusionPlex® Solid Tumor

FusionPlex® Acute Lymphoblastic Leukemia (ALL)

The FusionPlex® ALL panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex® Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex ALL contains 506 GSPs targeting 81 genes commonly mutated in acute lymphoblastic leukemia.

Platform

Description

Part Number

Storage Condition

Illumina®

Ion Torrent™

Archer® FusionPlex® ALL GSP1 - 8 reactions

SA0074-8-1

Archer® FusionPlex® ALL GSP2 - 8 reactions

SA0074-8-2

10X VCP Primer Mix

SA0126

-20°C ± 10°C

FusionPlex® Alk Ret Ros1 v2

The FusionPlex® ALK RET ROS1 v2 panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex® ALK RET ROS1 v2 contains 29 GSPs targeting 3 genes commonly mutated in many solid tumor type cancers.

Platform

Description

Part Number

Storage Condition

Illumina®

Ion Torrent™

Archer® FusionPlex® ALK RET ROS1 Panel v2 GSP1 - 8 reactions

SA0085

Archer -20°C ± 10°C ® FusionPlex® ALK RET ROS1 Panel v2 GSP2 - 8 reactions

SA0086

10X VCP Primer Mix

SA0126

-20°C ± 10°C

FusionPlex® Comprehensive Thyroid and Lung (CTL)

The FusionPlex® CTL panel is an optimized, balanced pool of gene-specific primers (GSP) that is used in conjunction with FusionPlex® Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex® CTL contains 203 GSPs targeting 36 genes commonly mutated in solid tumor type cancers.

Platform

Description

Part Number

Storage Condition

Illumina®

Ion Torrent™

Archer® FusionPlex® CTL Panel GSP1 - 8 reactions

SA0070-8-1

Archer -20°C ± 10°C ® FusionPlex® CTL Panel GSP2 - 8 reactions

SA0070-8-2

10X VCP Primer Mix

SA0126

-20°C ± 10°C

FusionPlex® Heme v2

The FusionPlex® Heme v2 panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex® Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex® Heme v2 contains 607 GSPs targeting 87 genes commonly mutated in hematological malignancies.

Platform

Description

Part Number

Storage Condition

Illumina®

Ion Torrent™

Archer® FusionPlex® Heme v2 GSP1 - 8 reactions

SA0073-8-1

SA0073-8-2

10X VCP Primer Mix

SA0126

Archer® FusionPlex® Heme v2 GSP2 - 8 reactions

-20°C ± 10°C

FusionPlex® Lung

The FusionPlex Lung panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex Lung contains 163 GSPs targeting 14 genes commonly mutated in lung cancer.

Platform

Description

Part Number

Storage Condition

Illumina®

Archer® FusionPlex® Lung GSP1 - 8 reactions

SA0126

Archer® FusionPlex® Lung GSP2 - 8 reactions

10X VCP Primer Mix

SA0166082

SA0166081

-20°C ± 10°C

FusionPlex® Myeloid

The FusionPlex® Myeloid panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex® Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex Myeloid contains 507 GSPs targeting 84 genes commonly mutated in myeloid malignancies.

Platform

Description

Part Number

Storage Condition

Illumina®

Ion Torrent™

Archer® FusionPlex® Myeloid GSP1 - 8 reactions

SA0075-8-1

SA0075-8-2

SA0126

Archer® FusionPlex® Myeloid GSP2 - 8 reactions

10X VCP Primer Mix

-20°C ± 10°C

FusionPlex® Lymphoma

The FusionPlex Lymphoma panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex Lymphoma contains 716 GSPs targeting 125 genes commonly mutated in lymphoid malignancies.

Platform

Description

Part Number

Storage Condition

Illumina®

Ion Torrent™

Archer® FusionPlex® Lymphoma GSP1 - 8 reactions

SA0077-8-1

SA0077-8-2

SA0126

Archer® FusionPlex® Lymphoma GSP2 - 8 reactions

10X VCP Primer Mix

-20°C ± 10°C

FusionPlex® Oncology Research

The FusionPlex® Oncology Research panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex® Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex® Oncology Research contains 393 GPSs targeting 75 genes commonly mutated in solid tumor type cancers.

Platform

Description

Part Number

Storage Condition

Illumina®

Ion Torrent™

Archer® FusionPlex® Oncology Research Panel GSP1 - 8 reactions

SA0072-8-1

SA0072-8-2

SA0126

Archer® FusionPlex® Oncology Research Panel GSP2 - 8 reactions

10X VCP Primer Mix

-20°C ± 10°C

FusionPlex® Pan-Heme

The FusionPlex Pan-Heme panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex Pan-Heme contains 1054 GSPs targeting 199 genes commonly mutated in hematological malignancies.

Platform

Description

Part Number

Storage Condition

Illumina®

Ion Torrent™

Archer® FusionPlex® Pan-Heme GSP1 - 8 reactions

SA0076-8-1

SA0076-8-2

SA0126

Archer® FusionPlex® Pan-Heme GSP2 - 8 reactions

10X VCP Primer Mix

-20°C ± 10°C

FusionPlex® Sarcoma

The FusionPlex Sarcoma panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex Sarcoma libraries contain 148 GSPs targeting 26 genes commonly mutated in solid tumor type cancers.

Illumina®

Ion Torrent™

Archer® FusionPlex® Sarcoma Panel GSP1 - 8 reactions

SA0093

SA0094

SA0126

Archer® FusionPlex® Sarcoma Panel GSP2 - 8 reactions

10X VCP Primer Mix

-20°C ± 10°C

Platform

Description

Part Number

Storage Condition

FusionPlex® Solid Tumor

The FusionPlex® Solid Tumor panel is an optimized, balanced pool of gene-specific primers (GSPs) that is used in conjunction with FusionPlex® Reagents and Molecular Barcode (MBC) Adapters to produce targeted NGS libraries. FusionPlex Solid Tumor libraries contain 288 GSPs targeting 53 genes commonly mutated in solid tumor type cancers.