Cancer All-In-One Assays

SureSelect Cancer All-In-One Solid Tumor Assay

The SureSelect Cancer All-In-One solid tumor assay is a streamlined tumor NGS assay. This assay profiles a cancer panel of 98 genes clinically relevant to common solid tumor types for pertinent SNVs, indels, CNVs, and translocations. Solid tumor types of interest include lung, breast, ovarian, colorectal, and prostate.

These genes were selected to cover the somatic variants associated with these solid tumor types in the guidelines of National Comprehensive Cancer Network (NCCN), the College of American Pathologists (CAP), and the European Society for Medical Oncology (ESMO).

Features

  • All-in-one profiling of SNVs, indels, CNVs, and translocations relevant to multiple solid tumors from a single DNA sample of 50 ng or less

  • Compatible with FFPE and low-quality DNA samples

  • Streamlined workflow to achieve target-enriched NGS libraries from DNA within a day

  • Robust detection of somatic CNVs, including gene amplifications and deletions down to 15% tumor cells

  • High-sensitivity translocation detection by targeting translocation driver genes regardless of partner genes

  • Complementary data analysis supported by Agilent SureCall software

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