Cancer All-In-One Assays

SureSelect Cancer All-In-One Lung Assay

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The Agilent SureSelect Cancer All-In-One lung assay is a targeted NGS assay that analyzes a lung cancer panel of 20 genes relevant to NSCLC. Starting from 50 ng of DNA, four types of genomic variants, including SNVs, indels, CNVs, and translocations, are detected. This streamlined profiling of NSCLC also supports FFPE samples.

The target genes were selected to cover all genomic biomarkers in NSCLC, including the somatic variants associated with NSCLC in the guidelines of the National Comprehensive Cancer Network (NCCN), the College of American Pathologists (CAP), and the European Society for Medical Oncology (ESMO).

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Features

• All-in-one profiling of SNVs, indels, CNVs, and translocations relevant to NSCLC from a single DNA sample of 50 ng or less

• Compatible with FFPE and low-quality DNA samples

• Streamlined workflow to achieve target-enriched NGS libraries from DNA within a day

• Robust detection of somatic CNVs, including gene amplifications and deletions down to 15% tumor cells

• High-sensitivity translocation detection by targeting translocation driver genes regardless of partner genes

• Complementary data analysis supported by Agilent SureCall software